The Centers for Medicare & Medicaid Services (CMS) and the Hospital Readmission Reduction Program (HRRP) policies are aimed at reducing hospital readmissions as a potential solution to the $17 billion annual expense associated with these avoidable events. Our fully customized, turn-key, Virtual Transitions of Care clinic (VTOC) services extend the role of hospitalists or the primary care physician to coordinate care for their patients during an acute to post-acute transition of care. This service is vital to the readmission reduction strategy and to decreasing preventable post-discharge adverse events. Our collaborative effort consists of a multidisciplinary approach, utilizing a combination of interventions to eliminate avoidable adverse events. These interventions include multiple automated and nonautomated communication modalities utilizing tele-health and remote patient monitoring, pharmacy inpatient bedside or home delivery services with medication reconciliation, homecare services and, most important, early virtual face-to-face outpatient follow-up in the VTOC clinic, as studies have found these interventions to be the most successful.